Indicators are: Cognitive conditions, including memory and attention dysfunctions, as well as depression, are commonly associated with elevated cortisol, and may be early indicators of exogenous or endogenous Cushing's. Depression and anxiety disorders are also common.
Treatment will depend on the cause. Your doctor may prescribe a medication to help. Some medications decrease cortisol production in the adrenal glands or decrease ACTH production in the pituitary gland. Other medications block the effect of cortisol on your tissues. If you use corticosteroids, a change in medication or dosage may be necessary. Don't attempt to change the dosage yourself. You should do this under close medical supervision.
Medications to control excessive production of cortisol at the adrenal gland include ketoconazole (Nizoral), mitotane (Lysodren) and metyrapone (Metopirone). Mifepristone (Korlym) is approved for people with Cushing syndrome who have type 2 diabetes or glucose .
Test Method 1 : A cortisol urine test is a safe, painless procedure that only involves ordinary urination. Cortisol is measured in a urinary sample collected over a 24-hour period. Your doctor will give you special containers to use for collecting urine samples. They'll also explain how to collect the urine properly.
On the first day of the urine collection:
Urinate into the toilet after waking up.
Flush this first sample away.
After that, collect all urine in special containers and store them in a cool place.
On the second day of the urine collection:
Urinate into the container right after waking up. This will be the last sample.
Return the containers to the appropriate person as soon as possible.