Your doctor may order an estradiol test if female or male sex characteristics aren't developing at the normal rate. An estradiol level that's higher than normal indicates that puberty is happening earlier than usual. This is a condition known as precocious puberty.
Lower levels of estradiol may indicate late puberty. The test can help your doctor find out if there are problems with your adrenal glands. It can also help determine if treatment for hypopituitarism (decreased function of the pituitary gland) is working.
A doctor may order estradiol testing to look for causes of:
abnormal menstrual periods
abnormal vaginal bleeding
infertility in women
Your doctor may also order an estradiol test if your menstrual cycle has stopped and you're having symptoms of menopause. During and after menopause, a woman's body will gradually produce less estrogen and estradiol, contributing to the symptoms experienced during menopause. A test of your estradiol level can help your doctor determine if you are preparing to enter menopause or you are already going through the transition.
While improving detoxification and elimination of estrogen is important to keep estrogen levels in balance plus reducing down activity of the aromatase enzyme by supplementing with Zinc stops testosterone from getting converted to estrogen in men ƒ. We also have to look at other lifestyle factors to reduce estrogen levels. Reducing alcohol consumption can help to reduce estrogen levels in men and women, for some people this means reducing alcohol consumption but for others it maybe necessary to eliminate alcohol for a period of time, this will also help liver function. Estrogen's in the environment are also a major problem, these can be found in plastics (even BPA free ones!), cleaning products, personal care products, factory farmed meats, it's used so much in society it is hard to avoid but we can reduce our exposure and improve our detoxification.
Estrogen-replacement therapy might be used in combination with clomiphene (Clomid) to help improve cervical mucus or uterine lining to make the body more hospitable to pregnancy. IVF treatment with lupron flare protocol or assisted hatching to try to compensate for poor quality and/or quantity of ovarian reserve.
Because high estradiol levels indicate poor ovarian reserve and poor response to fertility medications, you and your fertility doctor may ultimately need to discuss whether IVF with your own eggs is a viable option for you and your partner. You may need to discuss the possibility of using a donor egg with IVF.