Syphilis tests are used to screen for and/or diagnose infection with Treponema pallidum, the bacterium that causes syphilis. For more details about syphilis infection, see the "What is being tested?" section.
The best way to prevent syphilis is to practice safe sex. Using condoms during any type of sexual contact is a good idea. In addition, it may be helpful to: avoid having sex with multiple partners use a dental dam (a square piece of latex) or condoms during oral sex avoid sharing sex toys get screened for sexually transmitted infections and talk to your partners about their results
Penicillin G, administered parenterally, is the preferred drug for treating persons in all stages of syphilis. The preparation used (i. e, benzathine, aqueous procaine, or aqueous crystalline), dosage, and length of treatment depend on the stage and clinical manifestations of the disease. Treatment for late latent syphilis and tertiary syphilis require a longer duration of therapy, because organisms theoretically might be dividing more slowly (the validity of this rationale has not been assessed). Longer treatment duration is required for persons with latent syphilis of unknown duration to ensure that those who did not acquire syphilis within the preceding year are adequately treated.