In this test the level of adenosine deaminase in blood is measured. If adenosine deaminase (ADA) is markedly elevated in pleural fluid in a person with signs and symptoms that suggest tuberculosis, then it is likely that the person tested has an M. tuberculosis infection in their pleurae. This is especially true when there is a high prevalence of tuberculosis in the geographic region where a person lives.
When there is a low prevalence of tuberculosis in a region, then a person may have tuberculosis or may have an ADA result that is elevated for another reason, such as cancer (particularly lymphomas), pulmonary embolus, sarcoidosis, or lupus. These other diagnoses are more likely if the ADA result is only mildly or moderately elevated.
A person with a low ADA level is unlikely to have tuberculosis in their pleurae. This does not rule out having the infection in other parts of their body.
If ADA is markedly elevated in fluid from another part of the body, such as peritoneal fluid or CSF, then there is an increased likelihood that tuberculosis is present in this area.
Doctor will prescribe you mediaction accordingly after the test is conducted. Besides that you are suppose to maintain perosnal hygiene by covering your mouth covered whenever you cough or sneeze. Always remeber to wash your hands after sneezing or coughing.
When TB bacteria become active (multiplying in the body) and the immune system can’t stop the bacteria from growing, this is called TB disease. TB disease will make a person sick. People with TB disease may spread the bacteria to people with whom they spend many hours.
It is very important that people who have TB disease are treated, finish the medicine, and take the drugs exactly as prescribed. If they stop taking the drugs too soon, they can become sick again; if they do not take the drugs correctly, the TB bacteria that are still alive may become resistant to those drugs. TB that is resistant to drugs is harder and more expensive to treat.
TB disease can be treated by taking several drugs for 6 to 9 months. There are 10 drugs currently approved by the U. S. Food and Drug Administration (FDA) for treating TB. Of the approved drugs, the first-line anti-TB agents that form the core of treatment regimens are:
Test Method 1 : The level of adenosine deaminase (ADA) in sputum and effusion liquids was used for the diagnosis of tuberculosis (TB). But it is not always possible to access these materials. The goal of this study is to assess the diagnostic value of serum ADA levels in pulmonary TB patients.
Report available : The TAT for this test is about 1 to days.
This test is ordered as one of several tests to help rule in or rule out TB as the cause of a person's symptoms, especially if the individual falls into a high-risk group, such as:
People with close contact with someone who has active infectious TB
Immigrants from areas of the world where the incidence of TB is high
Children younger than 5 years old who have a positive TB screening test
People who work with or are part of groups with high rates of infection, such as the homeless, IV drug users or confined populations, such as hospitalized patients, prisoners, and residents of nursing homes
People with weakened immune systems such as:
Those with HIV/AIDS
Those with chronic underlying conditions, including diabetes and kidney disease
Organ transplant recipients and others on immunosuppressant drugs