There are at present no vaccines to prevent CMV infection. For those who have close contact with children, especially pregnant women or women, simple measures like hand washing may help. Other measures include are not sharing eating utensils, avoidance of intimate contact with anyone who has a CMV infection etc. However, a mother with the infection is advised not to stop breast feeding as the benefits of breastfeeding are believed to outweigh the risks of passing CMV to the baby. Blood and organs before donation need to be screened for the virus to prevent spread.
The oral antiviral medication also may be used at home once the infection is under control and the patient is stable. Some of the drugs used include CMV-immune globulin (CMV-IVIG) and the antiviral drug Ganciclovir.